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opportunita' di mercato identificate

# Scheda: 
114

Peptidomimetic compounds or synthetic derivatives designed for the therapeutic treatment of all those cardiac pathological conditions whose cardiac contractility and/or rhythmicity is associated with dysfunction of intracellular calcium homeostasis. In particular, it is referred here to all those pathological disorders where such dysfunctions are due to alterations of the density and function of the L-type calcium channel (LTCC). For instance, acquired or genetic-based cardiac disease, such as diabetic cardiomyopathy and inherited arrhythmogenic disease (i.e.

# Scheda: 
114

Composti peptidomimetici o derivati sintetici per il trattamento terapeutico di tutte quelle condizioni patologiche (cardiache ma anche neuronali, oftalmiche, vascolari, e intestinali) associate a disfunzioni dell’omeostasi intra-cellulare dello ione calcio (Ca2+) e dipendenti da alterazioni dei canali del calcio di tipo L (LTCC).

Titolo tecnologia:

New Caspase-1 Inhibitors

# Scheda: 
109

A new class of non-covalent caspase-1 inhibitors. The synthesized low molecular weight non-peptidic molecules have shown neuroprotective activity and are able to cross the blood brain barrier. Such molecules are of interest to modulate the inflammatory process with potential therapeutic application for both acute and chronic neurodegenerative diseases but also for inflammatory based diseases as articular diseases, skin disorders, and bowel diseases.

Titolo tecnologia:

Nuovi Inibitori di Caspasi-1

# Scheda: 
109

Una nuova classe di inibitori non covalenti di Caspasi-1. Le molecole sintetizzate di natura non peptidica e con basso peso molecolare, hanno mostrato attività neuroprotettiva e sono risultate in grado di attraversare la barriera ematoencefalica. Tali molecole sono d’interesse per modulare il processo infiammatorio con potenziale applicazione terapeutica per patologie neurodegenerative sia acute che croniche ma anche per patologie infiammatorie articolari, della pelle, e del tratto digestivo.

Titolo tecnologia:

Image Inspector 1.0

# Scheda: 
106

La Stazione Sperimentale di Granicoltura per la Sicilia ha sviluppato alcuni applicativi per la valutazione di parametri morfo-colorimetrici di matrici agroalimentari, mediante la tecnologia dell’analisi d’immagine. Questa permette di ottenere misure oggettive per la valutazione di proprietà fisiche relative alla dimensione e forma, ma anche ai componenti del colore e della texture degli oggetti in esame, consentendo di annullare tutti gli errori di una valutazione visiva, soggettiva e personale.

Titolo tecnologia:

Image Inspector 1.0

# Scheda: 
106

The “Stazione Sperimentale di Granicoltura per la Sicilia” has developed some applications for the evaluation of morpho-colorimetric parameters of food products, by means of image analysis technology. These application software allow to obtain accurate and precise measurements of sample physical traits relating to size, shape, color and the texture, reducing erroneous assessments related to the subjective and personal visual evaluation.

# Scheda: 
67

The technology is based on the development of molecular markers suitable to the identification and quantification of the precious white truffle - Tuber magnatum Pico – in truffle-products in order to certify their quality to the consumer.

The identification of the truffle species is generally based on the features of their spores and peridium, but the identification in processed truffle-products as creams and butter can be ambiguous because of the drastic treatments to which truffles are exposed during the commercial preparation.

# Scheda: 
52

AIM: To design and validate a multiparametric platform that allows the simultaneous detection of multiple immunohistochemical markers for CRC, by combining different positive or negative indicators, with the aim of developing a diagnostic/prognostic tool more specific, than those currently available.

# Scheda: 
30

It is a technology which allows to register SAXS scanning microscopies: an hard X-ray beam, focused by  proper optics, illuminates consecutive area of a sample, with a 2D detector – placed at a proper distance from sample - registering the signal diffracted from each illuminated area, in the small angle scattering range (SAXS). At the end of the acquisition, data are composed together in quantitative microscopy, using specific crystallographic and statistic approaches.

# Scheda: 
28

Companies and research groups involved in the production and characterization of new materials, in particular drugs, are interested in the determination of the three-dimensional atomic structure of a molecule to understand the structure-property relationships of the material.

The IC-CNR team has the experimental and methodological know-how to characterize materials available in the form of microcrystalline powders. The proven skills are: